W obszarze głównych zainteresowań zespołu leży metodologia eksperymentów NMR, tj. wykorzystanie najnowszych osiągnięć matematyki w opracowywaniu metod rejestracji i przetwarzania danych eksperymentalnych.
Rezultatem prac są nowe metody pomiarów widm wielowymiarowych biomolekuł, dyfuzometrii oraz niestandardowe podejścia do spektroskopii małych cząsteczek. Laboratorium oferuje spektrometr wysokiej rozdzielczości grupom zainteresowanym współpracą w rozwiązywaniu problemów biologii, chemii i fizyki. Oprócz szerokiej gamy rozwiązań metodologicznych, laboratorium zapewnia możliwość skorzystania z bogatego wyposażenia spektrometru, mi.in specjalnych sond przeznaczonych do badań białek, ciała stałego czy zawiesin.
telefon: +48 22 55 43666
pokój: 00.186
Degrees: MSc (Chemistry and Biophysics), PhD (chemistry), DSc (Habilitation, Chemistry)
Titles: Assistant Professor at University of Warsaw, PhD, Dsc
Affiliation: Centre of New Technologies, University of Warsaw, Poland
Education
2005 – MSc. Degree in Chemistry at the University of Warsaw. Supervisor: prof. Wiktor Koźmiński.
2007 – MSc. Degree in Biophysics at the University of Warsaw. Supervisors: prof. Ryszard Stolarski and prof. Wiktor Koźmiński.
10.06.2009 – PhD in chemistry (Faculty of Chemistry, University of Warsaw)
08.02.2017 – Habilitation degree in chemistry (Faculty of Chemistry, University of Warsaw)
Employment
From 1.11.2009 – Employed at the University of Warsaw.
2010 – 2011 – Postdoc at Swedish NMR Center, University of Gothenburg, Sweden. Title of the project: “NMR toolbox for studying intrinsically disordered proteins“.
1.05.2011-15.04.2012 – Postdoc in TEAM programme project ”Towards new applications of NMR spectroscopy in chemical and biomolecular structural studies“ at the University of Warsaw
2012 – current – Head of Laboratory of NMR, Centre of New Technologies, University of Warsaw
Honors and Awards
2007 – Antoni Grabowski Award for PhD student in Chemistry
2008 – Stipend of the Foundation for Polish Science (START programme). Prolongation for 2009.
2009 – PhD Thesis ”Methods of fast acquisition of NMR spectra for structural studies” honoured by Faculty Council of the Faculty of Chemistry, University of Warsaw.
2010 – PhD Thesis “Methods of fast acquisition of NMR spectra for structural studies” awarded by Prime Minister of Poland Award for PhD Thesis.
2014 – Wojciech Świętosławski award of the 2nd grade by the Polish Chemical Society
2015 – Wiley Award for the best lecture in NMR spectroscopy: “Dynamic non-uniform sampling”
Current scientific interests
Methods of multidimensional NMR. Processing of non-stationary signals. Compressed sensing in spectroscopy and chemistry.
Paper reviewing
Reviewer in: ChemPhysChem, Journal of Magnetic Resonance, Journal of Biomolecular NMR, Magnetic Resonance in Chemistry, Concepts in Magnetic Resonance, RSC Advances, Springer-PLUS and grants of National Science Centre, Swiss National Science Foundation and French National Research Agency.
Overview of teaching activity
Introductory seminars in molecular spectroscopy
Laboratory courses in molecular spectroscopy, physics and physical chemistry
Popular science: lecture and laboratory practice for high-school students etc.
International courses in biomolecular NMR spectroscopy organized in Swedish NMR Centre, Masaryk University (Brno), Spronk Consultancy (Vilinius), Polish Academy of Sciences (Łodź) and at the University of Warsaw
Research projects
- KOLUMB stipend (Foundation for Polish Science): „NMR toolbox for studying intrinsically disordered proteins“ (2011)
- IUVENTUS PLUS grant (Ministry of Science and Higher Education), project: ”Reconstruction of NMR spectra from incomplete data with compressed sensing algorithms“ (2012-2014)
- SONATA-BIS 2 grant (National Centre of Science): ”Sparse and approximately-sparse representations in problems of NMR spectroscopy“ (2013-2018)
- HARMONIA 2 grant (National Centre of Science): ”Regularization algorithms for the processing of NMR spectra of metabolite mixtures“ (2013-2014)
- ”Inkubator Innowacyjności“ (Ministry of Science and Higher Education): ”Statusino – mobile application for monitoring status of NMR spectrometers“
- OPUS 9 grant (National Centre of Science): ”Time-resolved N-dimensional spectroscopy for monitoring of physical and chemical processes “ (2016-2018)
- HARMONIA 9 grant (National Centre of Science): ”Radon transform in NMR spectroscopy of proteins“ (2018-2021)
- FIRST TEAM grant (Foundation for Polish Science): ”Methods of non-stationary signal analysis for more sensitive NMR spectroscopy“ (2018-2021)
Selected Publications
- Kazimierczuk, Krzysztof, Wiktor Koźmiński, and Igor Zhukov. Two-dimensional Fourier transform of arbitrarily sampled NMR data sets. Journal of Magnetic Resonance, 179(2):323–328, 2006.
- Kazimierczuk, Krzysztof, Anna Zawadzka, Wiktor Koźmiński, and Igor Zhukov. Random sampling of evolution time space and Fourier transform processing. Journal of Biomolecular NMR, 36(3):157–168, 2006.
- Kazimierczuk, Krzysztof, Anna Zawadzka, Wiktor Koźmiński, and Igor Zhukov. Lineshapes and artifacts in Multidimensional Fourier Transform of arbitrary sampled NMR data sets. Journal of Magnetic Resonance, 188(2):344–356, 2007.
- Kazimierczuk, Krzysztof, Anna Zawadzka, Wiktor Koźmiński, and Igor Zhukov. Determination of spin-spin couplings from ultrahigh resolution 3D NMR spectra obtained by optimized random sampling and multidimensional fourier transformation. Journal of the American Chemical Society,130(16):5404–5405, 2008.
- Kazimierczuk, Krzysztof, Anna Zawadzka, and Wiktor Koźmiński. Optimization of random time domain sampling in multidimensional NMR. Journal of Magnetic Resonance, 192(1):123–130, 2008.
- Kazimierczuk, Krzysztof, Anna Zawadzka, and Wiktor Koźmiński. Narrow peaks and high dimensionalities: Exploiting the advantages of random sampling. Journal of Magnetic Resonance, 197(2):219–228, 2009.
- Anna Zawadzka-Kazimierczuk, Kazimierczuk, Krzysztof, and Wiktor Koźmiński. A set of 4D NMRexperiments of enhanced resolution for easy resonance assignment in proteins. Journal of Magnetic Resonance, 202(1):109–116, 2010.
- Kazimierczuk, Krzysztof, Anna Zawadzka-Kazimierczuk, and Wiktor Koźmiński. Non-uniform frequency domain for optimal exploitation of non-uniform sampling. Journal of Magnetic Resonance, 205(2):286–292, 2010.
- Kazimierczuk, Krzysztof, Jan Stanek, Anna Zawadzka-Kazimierczuk, and Wiktor Koźmiński. Random sampling in multidimensional NMR spectroscopy. Progress in Nuclear Magnetic Resonance Spectroscopy, 57(4):420–434, 2010.
- Motáčková, Veronika and Nováček, Jiri and Zawadzka-Kazimierczuk, Anna and Kazimierczuk, Krzysztof and Žídek, Lukas and Šanderová, Hanna and Krásný, Libor and Koźmiński, Wiktor and Sklenář, Vladimir. Strategy for complete NMR assignment of disordered proteins with highly repetitive sequences based on resolution-enhanced 5D experiments. Journal of Biomolecular NMR, 48(3):169–177, 2010.
- Kazimierczuk, Krzysztof and Vladislav Yu. Orekhov. Accelerated NMR spectroscopy by using compressed sensing. Angewandte Chemie – International Edition, 50(24):5556–5559, 2011.
- Kazimierczuk, Krzysztof and Vladislav Yu. Orekhov. A comparison of convex and non-convex compressed sensing applied to multidimensional NMR. J. Magn. Reson., 223:1–10, 2012.
- Mateusz Urbańczyk, Diana Bernin, Wiktor Koźmiński, and K. Kazimierczuk. Iterative thresholding algorithm for multiexponential decay applied to pgse nmr data. Analytical Chemistry, 85(3):1828–1833, 2013.
- Kazimierczuk, Krzysztof, Olivier Lafon, and Philippe Lesot. Criteria for sensitivity enhancement by compressed sensing: Practical application to anisotropic nad 2d-nmr spectroscopy. Analyst, 139(11):2702–2713, 2014.
- Mateusz Urbańczyk, Wiktor Koźmiński, and Kazimierczuk, Krzysztof. Accelerating diffusion-ordered nmr spectroscopy by joint sparse sampling of diffusion and time dimensions. AngewandteChemie – International Edition, 53(25):6464–6467, 2014.
- Wolfgang Bermel, Dass, Rupashree, Klaus-Peter Neidig, and Kazimierczuk, Krzysztof. Two-dimensional nmr spectroscopy with temperature-sweep. ChemPhysChem, 15(11):2217–2220, 2014.
- Maxim Mayzel, Kazimierczuk, Krzysztof, and Vladislav Yu. Orekhov. The causality principle in the reconstruction of sparse NMR spectra. Chemical Communications, 50(64):8947–8950, 2014.
- Dass, Rupashree, Wiktor Koźmiński, and Kazimierczuk, Krzysztof. Analysis of Complex Reacting Mixtures by Time-Resolved 2D NMR. Analytical Chemistry, 87(2):1337–1343, 2015.
- Kazimierczuk, Krzysztof and Vladislav Orekhov. Non-uniform sampling: post-Fourier era of NMR data collection and processing. Magnetic resonance in chemistry : MRC, 53(11):921–6, dec 2015.
- Ikenna Edward Ndukwe, Shchukina, Alexandra, Kazimierczuk, Krzysztof, and Craig Philip Butts. Rapid and safe ASAP acquisition with EXACT NMR. Chem. Commun., 2(2):303, 2016.
- Shchukina, Alexandra, Paweł Kasprzak, Dass, Rupashree, Michał Nowakowski, and Kazimierczuk, Krzysztof. Pitfalls in compressed sensing reconstruction and how to avoid them. Journal of Biomolecular NMR, pages 1–20, 2016.
- Dass, Rupashree, Paweł Kasprzak, and Kazimierczuk, Krzysztof. Quick, sensitive serial NMR experiments with Radon transform. Journal of Magnetic Resonance, 282:114–118, 2017. Pkt. MNiSW (2016):30
dr hab. Krzysztof Kazimierczuk , prof. ucz.
Postdoctoral Fellows:
dr Marek Bukowicki
dr Alexandra Shchukina
PhD students:
mgr Sylwia Jopa
mgr Ewa Nawrocka
mgr Paulina Putko
Students:
Weronika Wleciał
Tytuł | Kierownik projektu | Okres | Finansowanie |
---|---|---|---|
Nowe wymiary w spektroskopii NMR dla lepszej analizy chemicznej – od małych cząsteczek do białek | Krzysztof Kazimierczuk | 2020 - 2025 | OPUS 18, NCN |
Mieszaniny cieczy jonowych do zastosowań w superkondensatorach: harmonia elektrochemii, NMR i symulacji | Krzysztof Kazimierczuk | 2022 - 2025 | OPUS 20 LAP, NCN |
Methods of non-stationary signal processing for more sensitive NMR spectroscopy | Krzysztof Kazimierczuk | 2018 - 2022 | FIRST TEAM, FNP |
Transformacja Radona w spektroskopii NMR białek | Krzysztof Kazimierczuk | 2018 - 2022 | HARMONIA 9. NCN |
Szczegółowe „odciski palców” białek w spektroskopii NMR | Dariusz Gołowicz | 2020 - 2022 | PRELUDIUM 17, NCN |
Czasorozdzielcza N-wymiarowa spektroskopia dla monitorowania procesów fizycznych i chemicznych | Krzysztof Kazimierczuk | 2016 - 2020 | OPUS 9, NCN |
Rzadkie i prawie-rzadkie reprezentacje w problemach spektroskopii NMR | Krzysztof Kazimierczuk | 2013 - 2018 | SONATA BIS, NCN |
Krzysztof Durka, Krzysztof Kazimierczuk, Sergiusz Luliński
Microporous and Mesoporous Materials Volume 337, May 2022, 111914
Dariusz Gołowicz, Alexandra Shchukina, Krzysztof Kazimierczuk
Anal. Chem. 2022, 94, 25, 9114–9121
Shchukina, A., Małecki, P., Mateos, B., Nowakowski, M., Urbańczyk, M., Kontaxis, G., ... & Kazimierczuk, K.
Chemistry–A European Journal, 27(5), 1753-1767
Jacquet M, Izzo M, Osella S, Kozdra S, Michałowski PP, Gołowicz D, Kazimierczuk K, Gorzkowski MT, Lewera, A, Teodorczyk, M, Trzaskowski B, Jurczakowski R, Gryko DT*, Kargul J
Nanoscale, 13, 9773 - 9787
Ewa K. Nawrocka, Mateusz Urbańczyk, Kamil Kozińskia , Krzysztof Kazimierczuk
RSC Advances, 2021,11, 35321-35325
Yulia Pustovalova, Frank Delaglio, D. Levi Craft, Haribabu Arthanari, Ad Bax, Martin Billeter, Mark J. Bostock, Hesam Dashti, D. Flemming Hansen, Sven G. Hyberts, Bruce A. Johnson, Krzysztof Kazimierczuk, Hengfa Lu, Mark Maciejewski, Tomas M. Miljenović, Mehdi Mobli, Daniel Nietlispach, Vladislav Orekhov, Robert Powers, Xiaobo Qu, Scott Anthony Robson, David Rovnyak, Gerhard Wagner, Jinfa Ying, Matthew Zambrello, Jeffrey C. Hoch, David L. Donoho, Adam D. Schuyler
Magn. Reson., 2, 843–861, 2021
Paweł Kasprzak, Mateusz Urbańczyk, Krzysztof Kazimierczuk
Journal of Biomolecular NMR 2021, 75,401–416
Dariusz Gołowicz, Magdalena Kaźmierczak, Krzysztof Kazimierczuk
Magnetic Resonance in Chemistry 2021, 59(3), pp. 213–220
Krzysztof Kazimierczuk
Magnetic Resonance in Chemistry Volume 59, Issue 3, Pages 199 - 200
Ville-Veikko Telkki, Mateusz Urbańczyk, Vladimir Zhivonitko
Progress in Nuclear Magnetic Resonance Spectroscopy, Volumes 126–127, October–December 2021, Pages 101-120
Gołowicz, D., Kasprzak, P., Orekhov, V., & Kazimierczuk, K.
Progress in Nuclear Magnetic Resonance Spectroscopy.
Abdi, G., Filip, A., Krajewski, M., Kazimierczuk, K., Strawski, M., Szarek, P., ... & Szczurek, A.
RSC Advances, 10(66), 40019-40029
Abdi, G., Filip, A., Krajewski, M., Kazimierczuk, K., Strawski, M., Szarek, P., ... & Szczurek, A.
RSC Advances, 10(66), 40019-40029
Romero, J. A., Kazimierczuk, K., & Gołowicz, D.
Analyst, 145(22), 7406-7411
Gołowicz, D., Kaźmierczak, M., & Kazimierczuk, K.
Magnetic Resonance in Chemistry, 59(3), 213-220
Romero, J. A., Nawrocka, E. K., Shchukina, A., Blanco, F. J., Diercks, T., & Kazimierczuk, K.
Angewandte Chemie, 132(52), 23702-23705
Perlinska, A. P., Stasiulewicz, A., Nawrocka, E. K., Kazimierczuk, K., Setny, P., & Sulkowska, J. I.
PLoS computational biology, 16(5), e1007904
Kauffmann, C., Kazimierczuk, K., Schwarz, T. C., Konrat, R., & Zawadzka-Kazimierczuk, A.
Journal of biomolecular NMR, 74(4), 257-265
Kasprzak, P., Kazimierczuk, K., & Shchukina, A. L.
Bulletin of the Russian Academy of Sciences: Physics, 84(11), 1335-1340
Mames, A., Gołowicz, D., Pietrzak, M., Kazimierczuk, K., Szymański, S., & Ratajczyk, T.
ChemPhysChem, 21(6), 540-545
Gołowicz, D., Kasprzak, P., & Kazimierczuk, K.
Sensors, 20(5), 1325
Kazimierczuk, K., Kasprzak, P., Georgoulia, P. S., Matečko-Burmann, I., Burmann, B. M., Isaksson, L., ... & Orekhov, V. Y.
Chemical Communications, 56(93), 14585-14588
Urbańczyk, M., Shchukina, A., Gołowicz, D., & Kazimierczuk, K. (2019).
Magnetic Resonance in Chemistry, 57(1), 4-12.
Gołowicz, D., Kazimierczuk, K., Urbańczyk, M., & Ratajczyk, T. (2019).
ChemistryOpen, 8(2), 196-200
Shchukina, A., Kaźmierczak, M., Kasprzak, P., Davy, M., Akien, G. R., Butts, C. P., & Kazimierczuk, K.
Chemical Communications
Rytel M., Kasprzak P., Setny P. & Kazimierczuk K.
Physical Chemistry Chemical Physics, 35
Nawrocka, E. K., Kasprzak, P., Zawada, K., Sadło, J., Grochala, W., Kazimierczuk, K., & Leszczyński, P. J.
Analytical Chemistry, 91(17), 11306-11315.
Nawrocka, E. K., Kasprzak, P., Zawada, K., Sadło, J., Grochala, W., Kazimierczuk, K., & Leszczyński, P. J.
Analytical Chemistry, 91(17), 11306-11315.
Gołowicz, D., Urbańczyk, M., Shchukina, A., & Kazimierczuk, K. (2018).
Journal of Magnetic Resonance, 294, 1-6.
Shchukina, A., Urbańczyk, M., Kasprzak, P., & Kazimierczuk, K.
Concepts in Magnetic Resonance Part A, 46A(2)
Urbańczyk, M., Nowakowski, M., Koźmiński, W., & Kazimierczuk, K. (2017)
Journal of Biomolecular NMR, 1-7.
Shchukina, A., Kasprzak, P., Dass, R., Nowakowski, M., & Kazimierczuk, K. (2017).
Journal of biomolecular NMR, 68(2), 99-100.
Ndukwe, I., Shchukina, A., Zorin, V., Cobas, C., Kazimierczuk, K., & Butts, C. (2017).
ChemPhysChem
Dass, R., Grudzia̧ż, K., Ishikawa, T., Nowakowski, M., Dȩbowska, R., & Kazimierczuk, K. (2017).
Frontiers in microbiology, 8, 1306.
Dass, R., Kasprzak, P., & Kazimierczuk, K. (2017).
Journal of Magnetic Resonance, 282, 114-118.
Shchukina, A., Kasprzak, P., Dass, R., Nowakowski, M., & Kazimierczuk, K. (2017).
Journal of biomolecular NMR, 68(2), 79-98.
Shchukina, A., Kasprzak, P., Dass, R., Nowakowski, M., & Kazimierczuk, K. (2017).
Journal of biomolecular NMR, 68(2), 79-98.
Ndukwe, I., Shchukina, A., Zorin, V., Cobas, C., Kazimierczuk, K., & Butts, C. (2017).
ChemPhysChem, 18(15), 2081-2087.
Unnerståle, S., Nowakowski, M., Baraznenok, V., Stenberg, G., Lindberg, J., Mayzel, M., ... & Agback, T. (2016).
PloS one, 11(1), e0146496
Lasota, A., Frączak, O., Muchowska, A., Nowakowski, M., Maciejczyk, M., Ejchart, A., & Olma, A.
Chemical biology & drug design, 87(6), 824-832
Ndukwe, I. E., Shchukina, A., Kazimierczuk, K., Cobas, C., & Butts, C. P. (2016).
ChemPhysChem, 17(18), 2799-2803.
Urbańczyk, M., Bernin, D., Czuroń, A., & Kazimierczuk, K. (2016).
Analyst, 141(5), 1745-1752.
Dass, R., Kasprzak, P., Koźmiński, W., & Kazimierczuk, K. (2016).
Journal of Magnetic Resonance, 265, 108-116.
Ndukwe, I. E., Shchukina, A., Kazimierczuk, K., & Butts, C. P. (2016)
Chemical Communications, 52(86), 12769-12772.
Jaremko, Ł., Jaremko, M., Nowakowski, M., & Ejchart, A. (2015)
The Journal of Physical Chemistry B, 119(36), 11978-11987
Shchukina, A. L., Eremchev, I. Y., & Naumov, A. V. (2015)
Physical Review E, 92(3), 032102
Lesot, P., Kazimierczuk, K., Trébosc, J., Amoureux, J. P., & Lafon, O. (2015).
Magnetic Resonance in Chemistry, 53(11), 927-939
Kazimierczuk, K., & Orekhov, V.
Magnetic Resonance in Chemistry, 53(11), 921-926
Lasota, A., Frączak, O., Leśniak, A., Muchowska, A., Lipkowski, A. W., Nowakowski, M., ... & Olma, A. (2015).
Journal of Peptide Science, 21(2), 120-125.
Kazimierczuk, K., & Orekhov, V. (2015).
Magnetic Resonance in Chemistry, 53(11), 921-926.
Dass, R., Kozminski, W., & Kazimierczuk, K. (2014).
Analytical chemistry, 87(2), 1337-1343.
Kazimierczuk, K., & Kasprzak, P. (2014).
Sensors, 15(1), 234-247.
Mayzel, M., Kazimierczuk, K., & Orekhov, V. Y. (2014).
Chemical Communications, 50(64), 8947-8950.
Urbańczyk, M., Koźmiński, W., & Kazimierczuk, K. (2014).
Angewandte Chemie, 126(25), 6582-6585.
Kazimierczuk, K., Lafon, O., & Lesot, P. (2014).
Analyst, 139(11), 2702-2713.
Kazimierczuk, K., Lafon, O., & Lesot, P. (2014).
Analyst, 139(11), 2702-2713.
Bermel, W., Dass, R., Neidig, K. P., & Kazimierczuk, K. (2014).
ChemPhysChem, 15(11), 2217-2220.
Urbańczyk, M., Koźmiński, W., & Kazimierczuk, K. (2014).
Angewandte Chemie, 126(25), 6582-6585.
Bermel, W., Dass, R., Neidig, K. P., & Kazimierczuk, K. (2014).
ChemPhysChem, 15(11), 2217-2220.
Misiak, M., Koźmiński, W., Chmurski, K., & Kazimierczuk, K. (2013)
Magnetic Resonance in Chemistry, 51(2), 110-115.
Urbańczyk, M., Bernin, D., Koźmiński, W., & Kazimierczuk, K. (2013)
Analytical chemistry, 85(3), 1828-1833.
Kazimierczuk, K., Stanek, J., Zawadzka‐Kazimierczuk, A., & Koźmiński, W. (2013)
ChemPhysChem, 14(13), 3015-3025
Tytuł | Termin nadsyłania aplikacji |
---|---|
Stażysta podoktorski (starszy asystent)(CeNT-39.1-2023) | 31/10/2023 |
Stażysta podoktorski (CeNT-39-2023) | 21/08/2023 |
Doktorant (CeNT-24-2023) | 30/05/2023 |
Doktorant (CeNT-65-2022) | 20/01/2023 |
Student in the Laboratory of NMR Spectroscopy | 30/07/2021 |
PhD Student in the Laboratory of NMR Spectroscopy | 15/11/2020 |
Postdoc (starszy asystent) w Laboratorium Spektroskopii NMR | 30/09/2020 |
PhD Student in the Laboratory of NMR Spectroscopy | 28/08/2020 |
Stypendysta w Laboratorium Spektroskopii NMR | 28/07/2020 |
Postdoc (Starszy Asystent) w Laboratorium Spektroskopii NMR | 25/04/2020 |
Postdoc in the NMR spectroscopy | 12/12/2018 |
Post doc in the laboratory of NMR spectroscopy | 12/12/2018 |
PhD student to the Laboratory of NMR Spectroscopy | 16/05/2018 |