PhD student in the Laboratory of Experimental Medicine

Dziedzina: Cancer Biology


Title of the position: PhD student
Scientific discipline: cancer biology
Job type: Scholarship
Number of job offers: 1
Remuneration/Stipend amount/month: 4500
Position starts on: 01.08.2019
Maximum period of contract/stipend agreement: 36 months
Institution: Laboratory of Experimental Medicine
Project leader: Anna Marusiak
Project title: The importance of MLK4 signalling in the communication between breast cancer cells and tumour-associated macrophages
Project Description: The main objective of this project is to describe the role of MLK4-dependent communication between breast cancer cells and macrophages, which are the most abundant immune cells in tumour microenvironment. MLK4 is a serine/threonine kinase that plays an important role in various cellular processes including proliferation, differentiation, migration of cells. We have recently proven that MLK4 is highly expressed in breast carcinoma and that it contributes to invasive phenotype of breast cancer cells. In our new project, we will evaluate the role of MLK4 on the abundance and behaviour of immune cells, macrophages, in tumour surroundings.

Key responsibilities include:
1. Performing experimental research (including cell culture, 3D cell culture, molecular cloning, transfections, generation of stable cell lines, various phenotypic assays, in vivo mouse work)
2. Participation in group meetings, institute’s seminars, courses and conferences.
3. Preparation of posters and publications.
4. Preparing reports.
5. Studying literature on a regular basis.
6. Preparing a PhD thesis.

Profile of candidates/requirements:
1. Degree in biotechnology, medicine or similar field (or about to graduate until end of September 2019).
2. Have a strong background in cell biology and biology of cancer.
3. Have excellent written and oral communication skills in English .
4. Have good presentation skills (ideally having presented on international conferences).
5. Have been an author on scientific publications.
6. Show a good level of independence, self-reliability and motivation.
7. Have permission for participation in in vivo work (not essential).

Required documents:
1. Motivation letter.
2. CV.
3. A list of publications and conferences attended.
4. One letter of support from an academic supervisor.

We offer:
1. Possibility to work in a young, active team in an excellent scientific environment (access to the state-of-the-art equipment).
2. Mentoring in laboratory techniques and personal development.
3. Participation in conferences.

Please submit the following documents to: The required documents must be sent by e-mail in PDF format to before the deadline. The recruitment committee will interview selected candidates before making the final decision. The interview will take place one week after the deadline.

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Termin nadsyłania aplikacji: 30/06/2019

Słowa kluczowe: breast cancer