Postdoc in the Laboratory of Bioorganic Chemistry

Field: Bioorganic Chemistry

Results of the competition:

As a result of the conducted competition, the committee has selected Karolina Drążkowska, PhD, for the position.


Project title: Mammalian cell delivery of stable therapeutic mRNA packaged inside virus-like particles

Project description: mRNA has shown great potential as an attractive alternative to protein and gene therapy in a variety of disease models. However, further development of this therapeutic approach requires solving of a number of problems such as susceptibility of mRNA to enzymatic degradation, inefficient translation in vivo and shortage of methods for efficient and selective mRNA delivery. Cellular stability of mRNA (inside host cells as well as during the passage through cellular membranes) is a crucial problem for all mRNA therapeutic applications.

Key responsibilities include: Enzymatic synthesis chemically modified mRNAs by means of in vitro transcription method. Studies on translation efficiency of modified mRNAs in in vitro and in cellulo systems. Preparation of proteins necessary for project realization.

Profile of candidate/requirements: The competition is open to persons who meet the conditions specified in:
– Act of 20 July 2018 Law on higher education and science (Journal of
Laws of 2018, item 1668, as amended) and the Statutes of the
University of Warsaw;
– Regulations on the allocation of resources for the implementation of
tasks financed by the National Centre of Science for OPUS 17 grant;
The candidate must be a holder of Ph.D. in molecular biology, and specialist in mRNA biochemistry and cell culture experiments.

We offer: stimulating and friendly work environment, and a monthly salary in the amount of PLN 10 000 gross (about 6 000 – 7 000 net), contract for the duration of 36 months.
Position starts on 01.04.2020.

Required documents:
1. Cover letter addressed to the Rector of the University of Warsaw
2. Current curriculum vitae including a description of prior research experience;
3. A list of publications and conference presentations;
4. At least two reference contacts (with phone numbers and e-mails)
5. Information on the processing of personal data – the form is available at the University of Warsaw webpage:

Druki do pobrania/Formularze

6. Declaration confirming that the candidate has read and accepted the rules of conducting competitions, covered in the following documents:
Order of the Rector of UW No. 106
Par. 119, 122 of the UW Statutes Resolution No. 443 of 26 June 2019

Please submit the following documents to: j. by 12.03.2020

Results will be announced no later that 19.03.2020. Candidates will be informed about the results by email.

More information to be found here:


The competition is the first stage of the recruitment procedure for the position of academic teacher specified in the Statutes of the University of Warsaw, and its positive result is the basis for further proceedings. Following an initial screening of the applications, selected candidates will be contacted by e-mail for further recruitment steps.

To allow us to process your data, please include the following statement in your application:
I give permission to the University of Warsaw, registered at the address of ul. Krakowskie Przedmieście 26/28, 00-927 Warszawa, to process my personal data for the purposes of carrying out the recruitment procedure, choosing the employee, and entering into an employment contract with the University of Warsaw, if applicable. I have been informed about my legal rights and obligations in relation to these actions. I acknowledge that providing the aforementioned personal data is done by me on a voluntary basis.

Deadline: 12/03/2020

Tags: mRNA, virus-like particles, vaccines, cell delivery, immunological response