The Centre of New Technologies invites to a seminar by
Prof. Ian Collinson, School of Biochemistry, University of Bristol
”Mechanism of protein translocation through the bacterial Sec machinery”
New date: October 24th (Wednesday), 2018 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Prof. dr hab. Agnieszka Chacińska
Transport of proteins across the bacterial inner membrane occurs primarily at the SecY translocon. The drive for post-translational transport comes from ATP hydrolysis by SecA, and the trans-membrane proton motive force (PMF). However, the underlying mechanism for this coupling is unclear. In my talk I will summarise how we think this is achieved. I will also consider how common principles may operate in other transport systems, including those responsible for mitochondrial protein import