Centre of New Technologies invites to a seminar by
Institute of Informatics, University of Warsaw
Looking at chromosomal contacts at different scales
17th of May 2018 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Joanna Sułkowska
Abstract: Chromosomes in eukaryotic nucleus are tightly packed into highly non-random conformations that facilitate gene expression regulation by coordinated enhancer-promoter contacts and maintenance of active and inactive compartment maintenance. However, due to technical constraints we are unable to observe these contacts directly on a genome wide-scale. We are interested in development of computational methods for analysis of Chromosome Conformation Capture experimental data that allow us to look at chromosomal contacts and correlate these with gene expression changes dynamics.